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The 4D Nucleome Network aims to understand the principles behind the three-dimensional organization of the nucleus in space and time (the 4th dimension) and the role nuclear organization plays in gene expression and cellular function. The Network utilizes existing omics and imaging technologies as well as develop new ones to generate data and create resources to enable the study of the 4D Nucleome.

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Project Assessments (97)


Assessment Metrics
Target Rubric   NIH program name is available for querying NIH project name is available for querying The institution that created this dataset is available A biological assay is present and resolvable in CFDE-specified ontology (OBI) The tool has a unique name and an informative description. The tool can be freely downloaded or accessed from a webpage. The tool utilizes a community-accepted ontology. Tutorials for the tool are available on the tool’s homepage. Source code is shared in a public repository and is documented. Previous versions of the tool are made available. Contact information is provided for the creator(s) of the tool and information describing how to cite the tool is provided. The tool can be accessed programmatically through an API and follows community standards for open APIs. Licensing information is provided on the tool’s homepage. A standardized ID or accession number is used to identify the dataset. The dataset is described with metadata using a formal, broadly applicable vocabulary. Information is provided on the experimental methods used to generate the data. The dataset is hosted in an established data repository, if a relevant repository exists. The dataset can be downloaded for free from the repository. Version information is provided for the dataset. Contact information is provided for the creator(s) of the dataset. Information is provided describing how to cite the dataset. Licensing information is provided on the dataset’s landing page. The structure of the repository permits efficient discovery of data and metadata by end users. The repository uses a standardized protocol to permit access by users. The repository provides contact information for staff to enable users with questions or suggestions to interact with repository experts. Tools that can be used to analyze each dataset are listed on the corresponding dataset pages. The repository maintains licenses to manage data access and use. The repository hosts data and metadata according to a set of defined criteria to ensure that the resources provided are consistent with the intent of the repository. The repository provides documentation for each resource to permit its complete and accurate citation. A description of the methods used to acquire the data is provided. Version information is provided for each resource, where available. Licensing information is provided on the tools home page The tool has a unique name and an informative description The tool can be freely downloaded or accessed from a webpage ANISEED database Machine readable metadata Tutorials for the tool are available on the tool’s homepage Source code is shared in a public repository and is documented Contact information is provided for the creator(s) of the tool and information describing how to cite the tool is provided The tool can be accessed programmatically through an API and follows community standards for open APIs A standardized ID or accession number is used to identify the dataset A relevant anatomical part is present and resolvable in the UBERON Ontology A relevant disease is present and resolvable in the MONDO Ontology A relevant file type is present and resolvable in the EDAM Ontology A relevant taxonomy is present and resolvable in the NCBITaxon Ontology A relevant cell line is present and resolvable in the Cellosaurus Ontology A landing page exists and is accessible Globally unique identifier Machine-readable metadata Standardized metadata Resource identifier in metadata Open, Free, Standardized Access protocol Digital resource license Metadata license Do the Data repository use any Identifiers? Do the repository have metadata records/files describing the data? In which format data is described with metadata? Does data repository is registered in any Registry? Does the structure of the Repository allow discovery of data and metadata by end user? Does Data repository uses any protocol to allow access by user? Does the data repository provide public API? Do the data repository provide versioning information of datasets? Does Data repository uses Title for the data resource in Data?
4DN Jupyter Hub Tool - BETA The FAIRshake tool rubric
        yes (1.00) yes (1.00) yes (1.00) nobut (0.25) yes (1.00) no (0.00) yes (1.00) nobut (0.25) yes (1.00)                                           no (0.00)                                                        
4D Nucleome The FAIRshake repository rubric
                                            yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) yes (1.00) no (0.00)                                                                
4DN data portal The FAIRshake repository rubric
                                            yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yesbut (0.75) nobut (0.25) no (0.00)                                                                
4DN Visualization Workspace The FAIRshake tool rubric
        yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)                                           no (0.00)                                                        
MicroMeta - Beta tool The FAIRshake tool rubric
        yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) yes (1.00)                                           no (0.00)                                                        
4DN data portal Findable and Accessible FAIR Principles for Research Data Repositories
                                                                                                            yes (1.00) yes (1.00) yes (1.00) no (0.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) yes (1.00)
4DN Visualization Workspace Common Fund Tools Assessments
                                                              yes (1.00) yes (1.00) yes (1.00)   no (0.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)                                            
4DN Jupyter Hub Tool - BETA Common Fund Tools Assessments
                                                              yes (1.00) yes (1.00) yes (1.00)   yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)                                            
MicroMeta - Beta tool Common Fund Tools Assessments
                                                              yes (1.00) yes (1.00) yes (1.00)   yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) yes (1.00)                                            
single cell RNA-seq on hamster olfactory sensory neurons The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
single cell RNA-seq on hamster olfactory sensory neurons NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00)                               yes (1.00)                                           yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)                  
E/L repliseq on U2OS cells (2017-08-17) The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
sciATAC-seq on F123 cells The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
5C on 6Mb of chrX The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
DpnII-seq on K562 cells The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
Bru-seq on F121-9 mESCs The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
H3K4me2 - K562 The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
Dual color smFISH on fruit fly embryo (nuclear cycle 13) The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
single cell Hi-C on sorted haploid H129-1s The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
Live imaging of chromatin topology and transcription The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
RNA-seq of early embryos in vitro The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
TSA-seq SON in K562 - HS The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
NAD-seq on MEF cells (not crosslinked) The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)                                                                                  
TCC on IMR90 +/- Adenovirus The FAIRshake dataset rubric
                          yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)