4DN data portal

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The 4D Nucleome Network aims to understand the principles behind the three-dimensional organization of the nucleus in space and time (the 4th dimension) and the role nuclear organization plays in gene expression and cellular function. The Network utilizes existing omics and imaging technologies as well as develop new ones to generate data and create resources to enable the study of the 4D Nucleome.

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Project Assessments (97)


Assessment Metrics
Target Rubric   NIH program name is available for querying NIH project name is available for querying The institution that created this dataset is available A biological assay is present and resolvable in CFDE-specified ontology (OBI) A relevant anatomical part is present and resolvable in the UBERON Ontology A relevant disease is present and resolvable in the MONDO Ontology A relevant file type is present and resolvable in the EDAM Ontology A relevant taxonomy is present and resolvable in the NCBITaxon Ontology A relevant cell line is present and resolvable in the Cellosaurus Ontology A landing page exists and is accessible A standardized ID or accession number is used to identify the dataset. The dataset is described with metadata using a formal, broadly applicable vocabulary. Information is provided on the experimental methods used to generate the data. The dataset is hosted in an established data repository, if a relevant repository exists. The dataset can be downloaded for free from the repository. Version information is provided for the dataset. Contact information is provided for the creator(s) of the dataset. Information is provided describing how to cite the dataset. Licensing information is provided on the datasetÂ’s landing page. Globally unique identifier Machine-readable metadata Standardized metadata Resource identifier in metadata Open, Free, Standardized Access protocol Digital resource license Metadata license
sciRNA-seq on F123 cells The FAIRshake dataset rubric
                    yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)              
GAM on mouse brain cell types The FAIRshake dataset rubric
                    yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yesbut (0.75) yes (1.00) yes (1.00) no (0.00)              
E/L repliseq on U2OS cells (2017-08-17) NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
sciATAC-seq on F123 cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
5C on 6Mb of chrX NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
DpnII-seq on K562 cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
Bru-seq on F121-9 mESCs NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
H3K4me2 - K562 NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
Dual color smFISH on fruit fly embryo (nuclear cycle 13) NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
single cell Hi-C on sorted haploid H129-1s NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
Live imaging of chromatin topology and transcription NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
RNA-seq of early embryos in vitro NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
TSA-seq SON in K562 - HS NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
NAD-seq on MEF cells (not crosslinked) NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
TCC on IMR90 +/- Adenovirus NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
Hi-C and Micro-C on WTC-11 derived iPS cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
sciHi-C on F121-6 cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
RNA-DNA SPRITE on pSM33 mESCs NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
DNA FISH on Chr4 NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
DamID-seq on HCT116 cells (2018-10-22) NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
16-fraction Repli-seq on H1-hESC NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
TRIP on K562 cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
Immunofluorescence on synchronyzed HeLa cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)
HiChIP-seq on NIH-3T3 cells NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric
yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00)             yes (1.00)     yes (1.00) yes (1.00) yes (1.00) yes (1.00) yes (1.00) no (0.00) no (0.00)