LINCS: Assessment of NIH Common Fund Resources with C2M2
Tags: nihcommonfund
URL(s):
- https://commonfund.nih.gov/lincs
- http://www.lincsproject.org/
- http://lincsportal.ccs.miami.edu/datasets/
- https://github.com/nih-cfde/FAIR/tree/master/LINCS
Project Assessments (2243)
| Assessment | Metrics | Date | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target | Rubric | NIH program name is available for querying | NIH project name is available for querying | Machine-readable metadata | The institution that created this dataset is available | A biological assay is present and resolvable in CFDE-specified ontology (OBI) | A relevant anatomical part is present and resolvable in the UBERON Ontology | Open, Free, Standardized Access protocol | A relevant disease is present and resolvable in the MONDO Ontology | A relevant file type is present and resolvable in the EDAM Ontology | A relevant taxonomy is present and resolvable in the NCBITaxon Ontology | A relevant cell line is present and resolvable in the Cellosaurus Ontology | Globally unique identifier | Digital resource license | Resource identifier in metadata | A landing page exists and is accessible | Metadata license | Contact information is provided for the creator(s) of the dataset. | ||
| Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| HKI-272 KINOMEscan-2 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Torkinib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| ZG-10 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Lapatinib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 7 of 15: End-point dose-response metrics for biological replicate 1. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| GSK429286A KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| ERK and Akt activation dynamics in MCF10A cells treated with the four core compounds. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MEMA AU565 Staining Set 100 (Lapatinib treatment) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| PI-103 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| SB590885 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Highly multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the COLO 858 melanoma cell line | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| SKI-606 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Gefitinib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MGH (CMT) Growth Inhibition Assay Protocol (3 compound doses) -- DNA Staining | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| WYE-125132 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| XMD8-85 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Moerke 3 Color Apoptosis | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with 8 small molecule perturbagens. Dataset 6 of 6: Nuclear fluorescent intensity measurements at 72 hr. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| HG-14-8-02 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| JNK-IN-11 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
