LINCS: Assessment of NIH Common Fund Resources with C2M2
Tags: nihcommonfund
URL(s):
- https://commonfund.nih.gov/lincs
- http://www.lincsproject.org/
- http://lincsportal.ccs.miami.edu/datasets/
- https://github.com/nih-cfde/FAIR/tree/master/LINCS
Project Assessments (2243)
| Assessment | Metrics | Date | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target | Rubric | NIH program name is available for querying | NIH project name is available for querying | Machine-readable metadata | The institution that created this dataset is available | A biological assay is present and resolvable in CFDE-specified ontology (OBI) | A relevant anatomical part is present and resolvable in the UBERON Ontology | Open, Free, Standardized Access protocol | A relevant disease is present and resolvable in the MONDO Ontology | A relevant file type is present and resolvable in the EDAM Ontology | A relevant taxonomy is present and resolvable in the NCBITaxon Ontology | A relevant cell line is present and resolvable in the Cellosaurus Ontology | Globally unique identifier | Digital resource license | Resource identifier in metadata | A landing page exists and is accessible | Metadata license | Contact information is provided for the creator(s) of the dataset. | ||
| SB590885 KiNativ -- dose response experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| DCC-2036 KiNativ -- single dose experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| PLX-4720 KiNativ -- dose response experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| L1000 Dataset -small molecule perturbagens- LINCS Phase 1 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| iMN (Exp 2) - ALS, SMA and Control (unaffected) iMN cell lines differentiated from iPS cell lines using a long differentiation protocol - ATAC-seq | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| L1000 Dataset -small molecule, CRISPR perturbagens- LINCS Phase 2 (December 2015) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| L1000 Dataset -small molecule perturbagens- LINCS Phase 2 (June 2015) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| iPSC (Exp 1) - ALS, SMA and Control (unaffected) subject-derived iPSC lines - SWATH-MS | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| iMN (Exp 2) - ALS, SMA and Control (unaffected) iMN cell lines differentiated from iPS cell lines using a long differentiation protocol - Proteomics | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (1.00) | yesbut (0.75) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | nobut (0.25) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | maybe (0.50) | Sep 25, 2019 |
| XMD11-85h KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MEMA HMEC122L Staining Set 4 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 12 of 15: Time-dependent mean normalized growth rate inhibition values for biological replicate 3. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Drug-drug synergy results from titration experiments | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MEMA PC3 Staining Set 3 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| PHA-665752 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MEMA HMEC240L Staining Set C | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Viability and apoptosis measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (viability/apoptosis dataset 1 of 2) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| HG-6-64-1 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MGH (CMT) Growth Inhibition Assay Protocol (9 compound doses: 8 nM to 0.03125 nM) -- DNA Staining | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MGH (CMT) Growth Inhibition Assay Protocol (9 compound doses: 10.24 uM to 0.04 uM) -- DNA Staining | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Phosphorylation state and protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (immunofluorescence dataset 1 of 4) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| GSK1059615 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MEMA MCF10A Staining Set C | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
