
LINCS: Assessment of NIH Common Fund Resources with C2M2
Tags: nihcommonfund
URL(s):
- https://commonfund.nih.gov/lincs
- http://www.lincsproject.org/
- http://lincsportal.ccs.miami.edu/datasets/
- https://github.com/nih-cfde/FAIR/tree/master/LINCS
Project Assessments (2243)
Assessment | Metrics | Date | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Target | Rubric | NIH program name is available for querying | NIH project name is available for querying | Machine-readable metadata | The institution that created this dataset is available | A biological assay is present and resolvable in CFDE-specified ontology (OBI) | A relevant anatomical part is present and resolvable in the UBERON Ontology | Open, Free, Standardized Access protocol | A relevant disease is present and resolvable in the MONDO Ontology | A relevant file type is present and resolvable in the EDAM Ontology | A relevant taxonomy is present and resolvable in the NCBITaxon Ontology | A relevant cell line is present and resolvable in the Cellosaurus Ontology | Globally unique identifier | Digital resource license | Resource identifier in metadata | A landing page exists and is accessible | Metadata license | Contact information is provided for the creator(s) of the dataset. | ||
Tyrosine Kinase Inhibitor-induced cardiotoxicity in hiPSC derived cardiomyocytes - Proteomics | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
WH-4-023 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
MEMA HMEC240L Staining Set 4 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
VX-745 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
MEMA YAPC Staining Set 2 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
Dinaciclib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
LINCS MCF 10A Common Project: Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with 8 small molecule perturbagens. Dataset 5 of 6: Cytosolic fluorescent intensity measurements at 72 hr. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
Growth factor-induced FoxO3a nuclear-cytoplasmic pulsing dynamics of non-phosphorylatable reporters in mammary epithelial cell lines. Dataset 2 of 3: single-cell reporter pulsing metrics. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | maybe (0.40) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
iMN (Exp 2) - ALS, SMA and Control (unaffected) iMN cell lines differentiated from iPS cell lines using a long differentiation protocol - RNA-seq | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (0.84) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
PHA-767491 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
Aggregated ChEMBL bioactivity data (v20) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yesbut (0.72) | yes (1.00) | no (0.00) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
GSK-1363089 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
EGF-induced FoxO3a nuclear-cytoplasmic pulsing dynamics in mammary epithelial cell lines following treatment with increasing doses of a MEK inhibitor. Dataset 3 of 3: mean reporter pulsing metrics. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
WZ3105 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
XMD11-50 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
Aggregated Tox21 bioactivity data | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (0.80) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
OTSSP167 KiNativ -- single dose experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
MEMA HMEC122L Staining Set 1 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
CI-1033 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
JNK-IN-8 KiNativ -- single dose experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
BMS-540215 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |