LINCS: Assessment of NIH Common Fund Resources with C2M2
Tags: nihcommonfund
URL(s):
- https://commonfund.nih.gov/lincs
- http://www.lincsproject.org/
- http://lincsportal.ccs.miami.edu/datasets/
- https://github.com/nih-cfde/FAIR/tree/master/LINCS
Project Assessments (2243)
| Assessment | Metrics | Date | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Target | Rubric | NIH program name is available for querying | NIH project name is available for querying | Machine-readable metadata | The institution that created this dataset is available | A biological assay is present and resolvable in CFDE-specified ontology (OBI) | A relevant anatomical part is present and resolvable in the UBERON Ontology | Open, Free, Standardized Access protocol | A relevant disease is present and resolvable in the MONDO Ontology | A relevant file type is present and resolvable in the EDAM Ontology | A relevant taxonomy is present and resolvable in the NCBITaxon Ontology | A relevant cell line is present and resolvable in the Cellosaurus Ontology | Globally unique identifier | Digital resource license | Resource identifier in metadata | A landing page exists and is accessible | Metadata license | Contact information is provided for the creator(s) of the dataset. | ||
| TGX221 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| ZM-447439 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| KIN001-220 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| A549 cells -- High-throughput Secretomic Analysis of Single Cells | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | yes (0.80) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| ABT-869 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| GSK-461364A KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| EGF-induced FoxO3a nuclear-cytoplasmic pulsing dynamics in mammary epithelial cell lines following treatment with increasing doses of a MEK inhibitor. Dataset 2 of 3: single-cell reporter pulsing metrics. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Sensitivity measures of MDA-MB-231 and HME-1 cell lines to LINCS Pilot Phase TransCenter Project kinase inhibitors | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| AZ-628 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Proteomics dataset (January 2016) | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| KU63794 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Ribociclib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 9: Mean cell count and mean normalized growth rate inhibition values for biological replicate 3 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Ibrutinib KiNativ -- single dose experiment | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| THZ1 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Sunitinib KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| QL-X-138 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| BI-D1870 KINOMEscan | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| L1000 Dataset -small molecule perturbagens- LINCS Trans-Center Project | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 9: Mean cell count and mean normalized growth rate inhibition values for biological replicate 1 | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| MGH (CMT) Growth Inhibition Assay Protocol (9 compound doses: 32 uM to 0.125 uM) -- DNA Staining | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
| Tang Proliferation/Mitosis | NIH Common Fund Data Ecosystem (CFDE) FAIR Rubric |
|
no (0.00) | yes (1.00) | no (0.00) | yes (1.00) | nobut (0.25) | no (0.00) | yes (1.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | no (0.00) | yesbut (0.75) | yes (1.00) | yes (1.00) | yes (1.00) | Sep 25, 2019 |
