NIH Common Fund Data Ecosystem: LINCS (CFDE-LINCS) FAIR Rubric

A rubric for evaluating the FAIRness of LINCS Resource

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Rubric Assessments (33)


Assessment Metrics Date
Target Project   Contact information is provided for the creator(s) of the dataset. Globally unique identifier Machine-readable metadata Standardized metadata Resource identifier in metadata Open, Free, Standardized Access protocol Digital resource license Metadata license The institution that created this dataset is available A biological assay is present and resolvable in CFDE-specified ontology (OBI) A relevant anatomical part is present and resolvable in the UBERON Ontology A relevant disease is present and resolvable in the MONDO Ontology A relevant file type is present and resolvable in the EDAM Ontology A relevant taxonomy is present and resolvable in the NCBITaxon Ontology A relevant cell line is present and resolvable in the Cellosaurus Ontology A landing page exists and is accessible Relevant Drug or Small Molecule terms are resolvable in PubChem Relevant Gene IDs are resolvable as NCBI Entrez Genes
L1000 Dataset -small molecule, CRISPR perturbagens- LINCS Phase 2 (December 2015) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00)     Jun 23, 2021
LINCS chemical perturbagen signatures LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) nobut (0.25) nobut (0.25) no (0.00) no (0.00) maybe (0.48) yes (1.00) yes (0.88) nobut (0.25) Jun 23, 2021
Transcriptomics dataset (August 2015) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
PeptideModifiedSequence_A375_f53da3_NoNAs_n288x5203 LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
Perturbational proteomic and transcriptional profiles of drug perturbations from Broad Institute LINCS Proteomic Characterization Center for Signaling and Epigenetics and Broad Institute LINCS Center for Transcriptomics LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00)     Jun 23, 2021
Transcriptomics dataset (June 2015) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
LINCS consensus gene (CGS) knockdown signatures LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) nobut (0.25) nobut (0.25) no (0.00) no (0.00) maybe (0.48) yes (1.00) maybe (0.52)   Jun 23, 2021
Broad Institute L1000 Connectivity Map and RNAseq gene expression profiles on tissue samples from the GTEx project LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
LINCS L1000 Chemical Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (0.99) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.47) yes (1.00)     Jun 23, 2021
iPSC (Exp 1) - ALS, SMA and Control (unaffected) subject-derived iPSC lines - RNA-seq LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
LINCS L1000 shRNA Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.49) yes (1.00)     Jun 23, 2021
LINCS L1000 CRISPR Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.50) yes (1.00)     Jun 23, 2021
L1000 Dataset -small molecule perturbagens- LINCS Phase 1 LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00)     Jun 23, 2021
VMSiteFlankCentric_A375_f53da3_NoNAs_n288x4433 LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
LINCS gene overexpression signatures LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) nobut (0.25) nobut (0.25) no (0.00) no (0.00) maybe (0.50) yes (1.00) maybe (0.52)   Jun 23, 2021
GCP aggregated data - Chemical perturbations LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00)     Jun 23, 2021
LINCS targeted proteomics signatures LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.39) yes (1.00) yes (0.83) nobut (0.25) Jun 23, 2021
LINCS L1000 Antibody Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.50) yes (1.00)     Jun 23, 2021
Transcriptomics dataset (March 2016) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) no (0.00) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00) maybe (0.50)   Jun 23, 2021
LINCS L1000 siRNA Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.50) yes (1.00)     Jun 23, 2021
iMN (Exp 2) - ALS, SMA and Control (unaffected) iMN cell lines differentiated from iPS cell lines using a long differentiation protocol - RNA-seq LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
EDS-1014 LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) no (0.00) no (0.00)   no (0.00) nobut (0.25) no (0.00) no (0.00) no (0.00) no (0.00) no (0.00) yes (1.00)     Jun 23, 2021
LINCS L1000 Ligand Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.50) yes (1.00)     Jun 23, 2021
P100 aggregated data - Chemical perturbations LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) no (0.00)   yes (1.00) yesbut (0.75) no (0.00)   yes (1.00) nobut (0.25) nobut (0.25) nobut (0.25) no (0.00) no (0.00) nobut (0.25) yes (1.00)     Jun 23, 2021
LINCS L1000 Overexpression Perturbations (2021) LINCS: Assessment of NIH Common Fund Resources with C2M2
  no (0.00) yes (1.00)   yes (1.00) yesbut (0.75) no (0.00)   no (0.00) nobut (0.25) yes (1.00) nobut (0.25) nobut (0.25) yes (1.00) maybe (0.49) yes (1.00)     Jun 23, 2021