Trans-Omics for Precision Medicine (TOPMed) Program

project

Trans-Omics for Precision Medicine (TOPMed), sponsored by the National Institutes of Health's National Heart, Lung and Blood Institute (NHLBI), is a program to generate scientific resources to enhance our understanding of fundamental biological processes that underlie heart, lung, blood and sleep disorders (HLBS). It is part of a broader Precision Medicine Initiative, which aims to provide disease treatments that are tailored to an individual’s unique genes and environment. TOPMed will contribute to this initiative through the integration of whole-genome sequencing (WGS) and other –omics (e.g., metabolic profiles, protein and RNA expression patterns) data with molecular, behavioral, imaging, environmental, and clinical data. In doing so, this program seeks to uncover factors that increase or decrease the risk of disease, identify subtypes of disease, and develop more targeted and personalized treatments.

Tags: Next generation sequencing Whole genome sequencing Omics Precision Medicine

URL(s):

View Analytics View Assessments

Associated Digital Objects (27)

Framingham Cohort

data

DCPPC

Genetic Epidemiology of COPD (COPDGene)

data

DCPPC

Women's Health Initiative

data

DCPPC

Multi-Ethnic Study of Atherosclerosis (MESA) Cohort

data

DCPPC

Atherosclerosis Risk in Communities (ARIC) Cohort

data

DCPPC

NHLBI Cleveland Family Study (CFS) Candidate Gene Association Resource (CARe)

data

DCPPC

CARDIA Cohort

data

DCPPC

Jackson Heart Study (JHS) Cohort

data

DCPPC

Cardiovascular Health Study (CHS) Cohort

data

DCPPC

NHLBI TOPMed: Genes-environments and Admixture in Latino Asthmatics (GALA II) Study

data

DCPPC

NHLBI TOPMed: Study of African Americans, Asthma, Genes and Environment (SAGE) Study

data

DCPPC

Create New Digital Object