Trans-Omics for Precision Medicine (TOPMed) Program

project

Trans-Omics for Precision Medicine (TOPMed), sponsored by the National Institutes of Health's National Heart, Lung and Blood Institute (NHLBI), is a program to generate scientific resources to enhance our understanding of fundamental biological processes that underlie heart, lung, blood and sleep disorders (HLBS). It is part of a broader Precision Medicine Initiative, which aims to provide disease treatments that are tailored to an individual’s unique genes and environment. TOPMed will contribute to this initiative through the integration of whole-genome sequencing (WGS) and other –omics (e.g., metabolic profiles, protein and RNA expression patterns) data with molecular, behavioral, imaging, environmental, and clinical data. In doing so, this program seeks to uncover factors that increase or decrease the risk of disease, identify subtypes of disease, and develop more targeted and personalized treatments.

Tags: Next generation sequencing Whole genome sequencing Omics Precision Medicine

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Associated Digital Objects (27)

Framingham Cohort

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Genetic Epidemiology of COPD (COPDGene)

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Women's Health Initiative

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Atherosclerosis Risk in Communities (ARIC) Co...

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CARDIA Cohort

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Jackson Heart Study (JHS) Cohort

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Cardiovascular Health Study (CHS) Cohort

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NHLBI TOPMed: Genes-environments and Admixtur...

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NHLBI TOPMed: Study of African Americans, Ast...

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