{"id":40199,"projects":[86],"description":"Multi-scale rabbit cardiac electrophysiology models\r\nThe workflow integrates multistep single-cell, 1D and 2D model simulations in a single automated process. The model formulation for ventricular cells from rabbits (Soltis-Saucerman*) was implemented in the workflow. The model contains beta-adrenergic signaling pathways, and the firing rate model (unpublished Lewis model).\r\n\r\nReference:\r\n\r\n*Soltis, A. R., & Saucerman, J. J. (2010). Synergy between CaMKII substrates and ?-adrenergic signaling in regulation of cardiac myocyte Ca2+ handling. Biophysical journal, 99(7), 2038-2047.\r\n\r\nThis work is also based on previous research using Kepler flows to model cardiac physiology: https://data.sparc.science/browse/#/datasets/23.","image":"https://discover.blackfynn.com/dataset-assets/4/18/banner.jpg","tags":"simcore, osparc, computational workflows","type":"data","title":"Multi-scale rabbit cardiac electrophysiology models","url":"https://discover.blackfynn.com/datasets/4","authors":[149],"rubrics":[]}